In addition to being a centre for clinical rehabilitation, Atrium is a hub for translational research.
At the heart of Atrium Health is a culture of applied clinical research with many staff involved in local, national and international research projects.
Atrium co-ordinates and delivers clinical research for numerous academic partners in addition to undertaking their own clinical trials led by Stuart Ennis and Gordon McGregor.
Rehabilitation Exercise and psycholoGical support After covid-19 Infection (REGAIN) trial
Chief investigator: Dr Gordon McGregor
This £1.2 million national clinical trial is being delivered at Atrium Health on behalf of UHCW NHS Trust and the University of Warwick Clinical Trials Unit. This clinical trial will help inform the Department of Health about the best treatment for people recovering from the long-term effects of COVID-19.
535 people who are still struggling months after being ill with COVID-19 will be recruited from all over the country and given one of two treatments to find which is better for helping recovery.
For more information follow these links:
https://dev.fundingawards.nihr.ac.uk/award/NIHR132046
https://warwick.ac.uk/fac/sci/med/research/ctu/trials/regain/
Supervised Pulmonary Hypertension Exercise Rehabilitation (SPHERe) trial
Chief investigator: Dr Gordon McGregor
Pulmonary hypertension is a disabling long-term condition that can greatly reduce quality of life. Many people develop it secondary to other long-term conditions like heart failure and COPD. Despite the potential benefits of exercise for this group, online supervised exercise programmes have not been evaluated.
Atrium Health will be the host site and will lead the delivery of this multi-centre £1.3 million national clinical trial, in collaboration with UHCW NHS Trust and the University of Warwick Clinical Trials Unit.
For more information see these links:
https://www.fundingawards.nihr.ac.uk/award/17/129/02
https://warwick.ac.uk/fac/sci/med/research/ctu/trials/sphere/
https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-020-01182-y
Postural tachycardia syndrome exercise (PULSE) study
Chief investigator: Dr Gordon McGregor
Postural Orthostatic Tachycardia Syndrome (POTS) can seriously effect well-being and quality of life. People with POTS have an abnormal heart rate rise when they stand up, with symptoms including palpitations, dizziness, fainting, and long-lasting fatigue.
The PULSE study, funded by a £190,000 grant from the British Heart Foundation, aims to find out if people with POTS will enrol on, and complete, a supervised physical activity programme. The project will be run at Atrium Health in collaboration with Coventry University and UHCW NHS Trust.
For more information see these links:
http://pulse-project.coventry.ac.uk
https://pilotfeasibilitystudies.biomedcentral.com/articles/10.1186/s40814-020-00702-1
High Intensity Interval Training In pATiEnts with intermittent claudication (INITIATE) study
Chief investigator: Prof Ian Chetter
Arterial disease in the legs is a common condition which severely limits walking ability and quality of life. This study will assess whether "high intensity" exercise programmes are safe and well tolerated, and effective in improving symptoms, fitness and quality of life.
The INITIATE study, funded by a £150,000 NIHR grant will enrol people on a HIIT programme at Atrium Health in collaboration with Hull University Hospitals NHS Trust and Coventry University.
For more information follow these links:
https://fundingawards.nihr.ac.uk/award/PB-PG-0418-20014